CFLAR and non-small cell lung carcinoma: This was evidenced by the reduction of c-FLIP (Caspase-Like Apoptosis Regulatory Protein) and caspase-8 as well as the altered expression of intrinsic apoptosis signaling proteins Bax (BCL2 Associated X, Apoptosis Regulator) and Mcl-1 (MCL1 Apoptosis Regulator, BCL2 Family Member), i.e., an anti-apoptosis protein overexpressed in NSCLC [36].