HCN2 and ileus: Expression changes in mechanosensitive ion channels were examined, and the down-regulation of hyperpolarization-activated and cyclic nucleotide-gated 2 channel (HCN2) during the development of intestinal edema and subsequent ileus was discovered (microarray data can be found at (http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc_GSE13193; accessed on 1 April 2023) [19].