By experimental screening, as shown in Figure 11, compound 47 showed excellent inhibition activity of cell proliferation against A549, MCF-7, and Hela cancer cell lines with IC50 values of 0.20 ± 0.05 μM, 1.25 ± 0.11 μM, and 1.03 ± 0.24 μM, and potently inhibited PI3K and mTOR kinases with IC50 values of 7.0 and 48 nM, respectively. The gene discussed is MTOR; the disease is cancer.