Furthermore, increased expression of proteins related to cellular proliferation pathways, such as AKT (also known as protein kinase B), ERK (extracellular signal-regulated kinase), CREB (cAMP-responsive element binding protein), and c-JNKs (c-Jun N-terminal kinases), has been reported in malignant ascites, detected via protein lysate microarrays [31]. The gene discussed is CREB1; the disease is cancer.