SOCS3 and triple-negative breast carcinoma: miR-483-5p has also been found to have a carcinogenic role in triple-negative breast cancer in that it inhibits SCOS3 (suppressor of cytokine signaling 3) gene expression that may trigger the pathway of STAT3, NF-κB, and primary inflammatory cytokines such as TNF-α, IL-6, MCP-1, and IL-1β [49].