NEAT1 and Parkinson disease: NEAT1 expression was significantly increased by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in both cell and mouse models of PD; NEAT1 promoted MPTP-induced autophagy by stabilizing PINK1 protein, and the knockdown of NEAT1 suppressed autophagy and alleviated dopaminergic neuronal injury [129].