TGFB1 and Hepatic fibrosis: Additionally, it is composed of Salvia miltiorrhiza, Prunus davidiana, Schisandra chinensis, Pinus massoniana, and Gynostemma pentaphyllum, etc. Additionally, FZHY has been demonstrated to improve liver fibrosis by targeting more than one molecule, like the TGF-β/Smad signaling pathways and TNF-α-induced apoptosis of hepatocytes [135,136].