CXCL8 and HIV-1 infection: A decreased secretion of Th1 cytokines such as IL-2 and antiviral IFN-γ, and an increased secretion of Th2 cytokines IL-4 and IL-10, and proinflammatory cytokines IL-1, IL-6, IL-8, and TNF-α have been reported in HIV-1 infection [115].