In addition, the decrease in the miR-34a-3p-MiD pathway induced by the upregulation of the dynamics of the mitochondrial proteins of 49 and 51 kDa (MiD49 and MiD51) in PAH SMCs increases DRP1-mediated fission and promotes vascular proliferation [65]. This evidence concerns the gene DNM1L and pulmonary arterial hypertension.