More recently, new genes have been recognized for their contribution to monogenic-dominant PD: Glucocerebrosidase (GBA), which encodes a lysosomal protein that degrades glucocerebroside [44], and Vacuolar Sorting Protein 35 (VPS35) [45,46], the chaperone of the Hsp40 family DNAJC13 [47], CHCHD2 [48], TMEM230 [49] and RIC3 [50]. This evidence concerns the gene GBA1 and Parkinson disease.