First, Figure 3D shows the externalized galectin-3 signals in NETs can be co-localized with the signals from the sera of patients with SLE; the limitation of this data is the possibility that the signals of anti-dsDNA antibodies or anti-NETs antibodies can be co-localized with the galectin-3 signals. This evidence concerns the gene LGALS3 and systemic lupus erythematosus.