Surprisingly, it did not show potent inhibitory activity against the c-KIT-independent GIST cell line GIST48B (GI50 ≥ 10 μM), FLT3 kinase activity, and did not exhibit antiproliferative activity against BCR-ABL-driven CML cell lines, such as K562 (GI50 ≥ 10 μM), MEG-01 (GI50 = 7.43 μM), and KU812 cells (GI50 = 6.71 μM). The gene discussed is KIT; the disease is gastrointestinal stromal tumor.