HMGB1 and metabolic dysfunction-associated steatotic liver disease: Khambu et al. reviewed the importance of HMGB1 in liver pathogenesis, reporting that the activation of HMGB1 and downstream signalling pathways are contributors to the pathogenesis of non-alcoholic fatty liver disease (NAFLD), alcoholic liver disease (ALD) and drug-induced liver injury (DILI) [91].