A cohort study by Liso et al. [126] on IBD patients receiving infliximab reported that supplementary administration of purple corn, which includes 0.5mg C3G equivalents/g DW, to their normal diet was associated with the downregulation of inflammatory biomarkers such as CRP, IFN-γ, TNF-α, IL-5, IL-9, IL-10, IL-12p70, and IL-17A, in CD but not UC patients. The gene discussed is TNF; the disease is inflammatory bowel disease.