We found that 17 genes were enriched in the Huntington’s disease (hsa05016) KEGG pathway; among them, 11 genes (TRAF2, MAPK8, BAX, CASP9, SP1, BBC3, CASP3, TP53, APAF1, CYCS, and CASP8) were shared between Huntington’s disease (hsa05016) and pathways in cancer (hsa05200) (Figure 1). The gene discussed is APAF1; the disease is juvenile Huntington disease.