We found that 17 genes were enriched in the Huntington’s disease (hsa05016) KEGG pathway; among them, 11 genes (TRAF2, MAPK8, BAX, CASP9, SP1, BBC3, CASP3, TP53, APAF1, CYCS, and CASP8) were shared between Huntington’s disease (hsa05016) and pathways in cancer (hsa05200) (Figure 1). This evidence concerns the gene APAF1 and Huntington disease.