TP53 and juvenile Huntington disease: We found that 17 genes were enriched in the Huntington’s disease (hsa05016) KEGG pathway; among them, 11 genes (TRAF2, MAPK8, BAX, CASP9, SP1, BBC3, CASP3, TP53, APAF1, CYCS, and CASP8) were shared between Huntington’s disease (hsa05016) and pathways in cancer (hsa05200) (Figure 1).