At least three genes from this list were involved in the formation of carcinomas, including breast carcinoma (CASP8, HSPA4, BCL2L11), prostate carcinoma (BCL2, CASP8, BCL2L11, ATM), and chronic lymphocytic leukemia (BCL2, CASP8, FAS, BCL2L11, BAK1). The gene discussed is CASP8; the disease is B-cell chronic lymphocytic leukemia.