In fact, a mutant OGG1, namely OGG1 S326C that has a lower threshold of inactivation by oxidant stress, was observed more frequently in patients with AML relapse [28.9 vs. 8.9%, odds ratio = 4.10, 95% confidence interval = 1.35–12.70, p = 0.01], and these patients exhibited a shorter relapse-free survival [124]. The gene discussed is OGG1; the disease is acute myeloid leukemia.