C. longa extracts containing bisacurone suppress the development of ethanol-induced liver injury [11,12] and non-alcoholic fatty liver disease (NAFLD) [13] in murine models by reducing serum levels of pro-inflammatory cytokines, such as IL-6 and TNF-α, and improving liver weight, fat accumulation, and levels of biochemical markers, such as serum cholesterol and aspartate aminotransferase (AST)/alanine aminotransferase (ALT). Here, IL6 is linked to metabolic dysfunction-associated steatotic liver disease.