In OC, TAMs are predominantly M2 macrophages that produce and secrete anti-inflammatory/immunosuppressive cytokines such as IL-10 and transforming growth factor beta 1(TGFB1) and chemokines (CCL17, CCL18, and CCL22) associated with tumor invasion, angiogenesis, metastasis, and early recurrence [25]. This evidence concerns the gene TGFB1 and neoplasm.