Our data showed that TELO2 downregulated the expression of FGFR3 in NHA and GBM8401 cells, which is consistent with the idea that genes negatively related to FGFR3 demonstrated tumor-related functions, such as mitosis and cell cycle, and FGFR3 correlated with relatively differentiated cellular function in gliomas. The gene discussed is FGFR3; the disease is central nervous system cancer.