Tagitinin C, Doxorubicin, and Withaferin A could induce NRF2 nuclear translocation and significantly increase the expression level of the HO-1 protein, which promotes lipid peroxidation and induces ferroptosis in cardiomyocytes, cancer cells, or neuroblastoma [54,55,56]. The gene discussed is HMOX1; the disease is neuroblastoma.