FLG and atopic eczema: miR-143: This molecule probably plays a role in the pathogenesis of atopic dermatitis by acting on IL-13, which reduces the level of expression of filaggrin, involucrin, and locrin via the STAT6 signaling pathway, thus impairing the epidermal barrier, which was confirmed in studies using primary normal human epidermal keratinocytes (NHEKs).