Although single-nucleotide polymorphism studies have not identified an association between PPARγ and antipsychotic-induced weight gain in schizophrenia patients with olanzapine and clozapine treatment [39,40], our previous study indicated that the activation of the hepatic Pparγ pathway was linked to the olanzapine-induced hepatic adipogenesis and lipid accumulation in the liver [24]. Here, PPARG is linked to schizophrenia.