When we adjusted the CRP-HHD outcome estimate by regressing for T2D and BMI, the OR was found to be 1.28 [1.07–1.53], p = 0.006; the OR became 1.14 [1.01–1.30], p = 0.039 when hypertension was added to this adjustment, while adding hypertension and CKD readjusted the OR to 1.19 [1.01–1.41], p = 0.038. The gene discussed is CRP; the disease is type 2 diabetes mellitus.