S-IGFBP-1 was inversely correlated with Homeostatic model assessment of IR (HOMA-IR), i.e., insulin resistance (r = −0.33, p < 0.001 acutely and r = −0.26, p < 0.001 after 3 months), and BMI (r = −0.25, p < 0.001 acutely and r = −0.28, p < 0.001 after 3 months). This evidence concerns the gene IGFBP1 and Insulin resistance.