Apart from its common use as a tumor marker in ovarian cancer, an abnormally high expression of serum CA-125 is also present in other neoplasms (breast, lung, uterus, and stomach, lymphangioleiomyomatosis) [73], in non-malignant pathologies (endometriosis, tuberculosis, urinary infections, peritonitis, pericarditis, cirrhosis), and physiological conditions (pregnancy, menstruation) [74]. The gene discussed is MUC16; the disease is neoplasm.