In this process, our findings also tend to confirm the important role of the subunit d of ATP synthase (encoded by (Atp5h/ATP5H), linked to the work by Chang et al., who reported the involvement of the overexpression of this subunit in venous invasion, distant metastasis of colon cancer and, finally, poor survival [41]. This evidence concerns the gene ATP5PD and malignant colon neoplasm.