ELK1 and neoplasm: In tumor cells, the downregulation of DNA methyltransferase (DNMT)1 expression results in silencing a transcription network regulating the G1-S transition, including forkhead box (FOX)M1, FOXD, FOXL, early growth response (EGR)1/2/3, peroxisome proliferator-activated receptor (PPAR)γ, ETS Like-1 protein Elk-1 (ELK1) and Jun family members [78,176].