EPCAM and cancer: Endothelial leukocyte adhesion molecule 1 (E-selectin) signaling in endothelial cells induces a non-canonical mesenchymal–epithelial transition (MET) phenotype in cancer cells, which begin to express EpCam and cytokeratin 14 (CK14) while continuing to express mesenchymal gene expression factors including snail family transcriptional repressor (Snail) 1/2, twist family bHLH transcription factor (Twist) 1/2, zinc finger E-box binding homeobox (Zeb) 1/2 and cancer stem cell marker Sox 2/9 [164].