In a mouse model, a minimally invasive procedure to remove human triple-negative cell line-generated xenograft tumors eliminated tumor-secreted factors, including IL-6, IL-8, VEGF, EGF, PDGF-AA, MIF, SerpinE1, M-CSF, focal adhesion, metalloprotease and apoptosis regulation processes [315]. This evidence concerns the gene CXCL8 and neoplasm.