Expression of the metastasis suppressor genes KISS-1, metastasis suppressor Kangai-1 (KAI1), mitogen-activated protein kinase (MKK)4/7 and NM23 nucleoside diphosphate kinase 1 (Nm23-H1) by cancer cells also promotes tumor dormancy at the metastatic site [170]. Here, NME1 is linked to cancer.