IL3RA and acute myeloid leukemia: Clinical studies: In 2019, Sun et al. decided to use the donor-derived second-generation anti-CD123 CAR-T cells combined with chemotherapy as the conditioning regimen for haploidentical HSCT in a patient with t(16;21) (p11;q22) AML relapse after allo-HSCT and a total of nine prior lines of ineffective therapy.