FLT3 and acute myeloid leukemia: The authors attributed the increased effectiveness of therapy after the inclusion of gilteritinib to the fact that gilteritinib not only increases the expression of FLT3 on AML cells, but it also, through its interaction with the noncanonical NF-κB2/Rel B signaling pathway, leads to an increase in the expression of NKG2DL on AML cells [74].