LEMD1 and cancer: Next, we analyzed the prognostic value of LEMD1 in pan-cancer and found that high expression of LEMD1 was significantly associated with worse OS rate in COAD (p = 0.047), KIRC (p = 0.0065), KIRP (p = 0.023) and PAAD (p = 0.0027) (Supplementary Figure S3B).