Another study using transcriptomes of two cohorts, GSE41258 and GSE32323, contained in The Cancer Genome Atlas (TCGA) analyzed differences in SLC4A4 expression between tumor and normal tissue, showed that SLC4A4 expression was lower in colon adenocarcinoma than in normal colon tissue, and suggested lower expression was associated with poor prognosis. This evidence concerns the gene SLC4A4 and colon adenocarcinoma.