We analyzed BRMS1 mRNA expression of 12 non-cancerous brain (NB) specimens (autopsy = 8; epilepsy surgery = 4), four patients with benign adult pilocytic astrocytoma WHO grade 1 (PA), 24 astrocytomas IDH mutant, CNS WHO grades 2 and 3 (in the following referred to as gliomas grade 2/3) and 78 GBM. This evidence concerns the gene BRMS1 and central nervous system cancer.