Other examples include THY1, which was also found among 25 differentially expressed genes as fibrosis steatohepatitis progressed through stages F2 to F4 in a large multicenter study [13], and MMP7, whose serum levels were independently associated with clinically significant fibrosis and improving the diagnostic performance of currently available tests in NAFLD patients [46]. This evidence concerns the gene MMP7 and metabolic dysfunction-associated steatotic liver disease.