MiRNAs can be readily detected in tumor biopsies, and they are also stable in body fluids due to being bound to lipoproteins, associated with the Argonaute 2 (Ago2) protein, packaged into microvescicles and other microparticles (such as apoptotic bodies, microvesicles, and exosome-like particles) as circulating miRNAs [92,93,94]. This evidence concerns the gene AGO2 and neoplasm.