MSH2 and hereditary nonpolyposis colon cancer: A cases series on FNMTC-HNPCC (N = 4) in LS showed two cases with papillary TC, respectively, a 47-year-old female with a history of HNPCC, EC, and OC carrying a germline MLH1 mutation (1858G>T/E620X) and a 34-year-old male with HNPCC carrying an MSH2 mutation; one case was a 39-year-old female with an anaplastic type and HNPCC, and one case was a 44-year woman with undifferentiated TC and HNPCC [49].