By using maspin levels in the four biological fluids, we developed algorithms for determination with a high probability of location (based on all four levels), TNM staging (also based on all four levels), size (based on whole-blood, tissue and urine levels), invasions (based on whole-blood levels), tumor grade (based on whole-blood and tissue levels) and mucus presence (based on whole-blood and saliva levels). This evidence concerns the gene SERPINB5 and neoplasm.