OGM analyses unveiled recurrent alterations involving novel genes of interest in AML, such as the KMT2A gene partial tandem duplication (7/41 AML cases), alterations of the MYB gene (3/41 AML cases), and rearrangement of the NUP98 gene (2/41 AML cases). The gene discussed is MYB; the disease is acute myeloid leukemia.