The bioinformatics study LASSO Cox regression that identified a critical risk signature for AML, consisting of the autophagy genes BAG3, CALCOCO2, CAMKK2, CANX, DAPK1, P4HB, TSC2, and ULK1, had excellent predictive power for AML prognosis [120]. The gene discussed is P4HB; the disease is acute myeloid leukemia.