Interestingly, we found that the Peli1 global knockout group showed more IL-6 released in the blood stream when compared to the WTCLP (706.8 ± 43 vs. 483.2 ± 24.01; pg/mL; n = 6; p < 0.0001) and CP1KO sepsis groups (706.8 ± 43 vs. 503.3 ± 10.59; pg/mL; n = 6; p = 0.0002). The gene discussed is IL6; the disease is Sepsis.