SOCS3 and melanoma: Comparing the four lists of DEG, we found that the expression of five genes: Ephrin-A1 (EFNA1), Suppressor of cytokine signaling 3 (SOCS3), Tropomodulin 1 (TMOD1), MYCN Proto-oncogene (MYCN), and Cytochrome P450 family 27 subfamily C member 1 (CYP27C1) was upregulated in microglia exposed to MCM from each of the four melanomas (Figure 1c).