Hence, this study aimed to further validate the role of the markers in TMZ-promoted cellular dormancy, to examine whether CCRL1, SLFN13, SKI, Cables1, and DCHS1 inherit a potential connection to the phenomenon of stemness in GBM, and investigate whether targeting (any of) these markers can improve the antitumor potential of TMZ. This evidence concerns the gene SLFN13 and glioblastoma.