Hence, this study aimed to further validate the role of the markers in TMZ-promoted cellular dormancy, to examine whether CCRL1, SLFN13, SKI, Cables1, and DCHS1 inherit a potential connection to the phenomenon of stemness in GBM, and investigate whether targeting (any of) these markers can improve the antitumor potential of TMZ. The gene discussed is SKI; the disease is glioblastoma.