Finally, CKD reprograms kinomes and upregulates serine/arginine-rich protein-specific kinase 3 (SRPK3) and choline kinase beta (CHKB) pathways in veins, and CKD reprograms vein transcriptomes and upregulates MYCN, AP1, and 11 other transcription factors. This evidence concerns the gene SRPK3 and chronic kidney disease.