In the case of CF, we and others have previously shown the generation of patient-specific hiPSCs [18,21], their genetic correction in vitro, and the application of CF-hiPSC-derived epithelial cells for High-Throughput (HT) screening to identify new modulators or drug testing of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) function [11,12,22]. The gene discussed is CFTR; the disease is cystic fibrosis.