By analyzing expression levels of ABC transporters in breast cancer patients treated with neoadjuvant chemotherapy (5-fluorouracil-, doxorubicin-, cyclophosphamide- and/or paclitaxel-based), ABCA7 was one of 22 ABC transporters being up-regulated in tumor tissues compared to paired non-neoplastic tissues [30]. This evidence concerns the gene ABCG2 and neoplasm.