In the last decade, data from epidemiological studies and meta-analyses [8], Mendelian randomization studies [9] and genome-wide association studies [10, 11] have ultimately demonstrated that elevated Lp(a) levels lead to a higher risk of cardiovascular disease in the population, mainly including but not limited to myocardial infarction, stroke, and peripheral arterial disease [12]. The gene discussed is LPA; the disease is cardiovascular disorder.