TASL and neoplasm: In conclusion, the correlation between TASL expression and the content of TIICs, in conjunction with the results of survival analysis, consistently suggested that TASL may contribute to the different prognosis of “cold” tumor LGG and “hot” tumors LUAD and SKCM, respectively, by influencing the infiltration of various TIICs in TME, especially TILs and TAMs.