Interestingly, we also found that most of the significantly enriched metabolic pathways were widely downregulated in the TASL high expression group of 20 types of cancers, such as “oxidative phosphorylation”, and “glutathione metabolism”, etc. In addition, TASL also affected several cancer-related pathways, including “cell adhesion molecule CAMs”, “hedgehog signaling pathway”, etc. These data suggest that TASL may influence cancer progression by regulating immunity, energy metabolism, and cell proliferation and metastasis, detailed information is shown in Supplementary Table 1. This evidence concerns the gene TASL and cancer.