We observed significant differences in BMI, NT-proBNP, history of alcohol intake, proportion of statin use, left ventricular end systolic diameter, left ventricular end diastolic volume, left ventricular end systolic volume, left ventricular mass index, and the prevalence of atrial fibrillation, coronary heart disease, chronic obstructive pulmonary disease, chronic kidney disease, diabetes, and hypertension among the three groups (details are shown in Table 2). This evidence concerns the gene NPPB and chronic obstructive pulmonary disease.