In 2 other cases, the malignant type changed after consultation with soft tissue pathologists and hemopathologists respectively; in case 10 it changed to spindle cell sarcoma (rhabdomyosarcoma, IHC strongly positive for muscle markers desmin and myoD1; negative for EMA, MART1, and CD99), and in case 110 it changed to lymphoma with further investigation is needed for typing (IHC: positive for CD3, CD2, and CD 20; negative for CD7 and EBV-encoded RNA). The gene discussed is DES; the disease is rhabdomyosarcoma.