CD8A and amyotrophic lateral sclerosis: However, while the CD3+, CD4+, CD8 + T-lymphocytes and the B-lymphocytes did not differ between ALS and DC, in the ALS patients the blood levels of the NK cells were significantly higher than in the controls (ALS, 236 cells/μl, IQR = 158–360, vs. DC, 174 cells/μl, IQR = 113–240, p < 0.001, Mann-Whitney Rank Sum Test).