In this current study, TGF-β1 and PDGF-AB increased PRO-C6 in both fibroblast types and PRO-C3 in dermal fibroblasts, while PRO-C3 was only increased by TGF-β1 in pulmonary fibroblasts IPF. This evidence concerns the gene TGFB1 and idiopathic pulmonary fibrosis.