As shown in Fig. 4, we corroborated the gene expression data by monitoring the expression of several activation markers, including CD25, CD40L, HLA-DR, CD28, CD38, CD44 and CD69, showing no significant modulation when CAR.CD19-T cells are stimulated by the lymphoma DAUDI cells in the presence of INFγ neutralization. This evidence concerns the gene CD38 and lymphoma.