Although we chose cell line clones harboring HIV-1 integration into introns of actively transcribed genes and cancer genes to recapitulate HIV-1 integration events in HIV-1+ individuals, these integration sites serve as biological replicates but not as a precise reflection of HIV-1 integration into enriched integration sites, such as BACH2, MRTFB, and STAT3 (Maldarelli et al. 2014; Yoon et al. 2020; Coffin et al. 2021; Mellors et al. 2021). This evidence concerns the gene MRTFB and cancer.